产品货号：
Z13449
中文名称：
Claudin 7/CLDN7抗体
英文名称：
Anti-Claudin 7/CLDN7 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Claudin 7/CLDN7 Antibody |
| 指标别名 | CEPTRL2;Claudin 7;CLDN 7;CLDN7;CPETRL2;Hs.84359 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IF,ICC/IF,FCM,ELISA |
| 基因名称 | CLDN7 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Claudin 7/CLDN-7 recombinant protein (Position:F92-V211). |
| 实际分子量 | 22KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Claudin-7 is a protein that in humans is encoded by the CLDN7 gene.This gene encodes a member of the claudin family.Claudins are integral membrane proteins and components of tight junction strands.Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets,and also play critical roles in maintaining cell polarity and signal transductions.This gene is expressed constitutively in the mammary epithelium throughout development,and might be involved in vesicle trafficking to the basolateral membrane.It is essential for NaCl homeostasis in distal nephrons.The knockout mice lacking this gene showed severe salt wasting,chronic dehydration,and growth retardation,and died within 12 days after birth.Alternatively spliced transcript variants have been found for this gene. |
| Uniprot ID | O95471 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | claudin 7 |
| 蛋白名全称 | Claudin-7 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Immunofluorescence (IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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